conclusion prevalence of p. aeruginosa producing esbl and mdr strains from our clinical samples and environment is still low. results the highest resistance rates from the isolated p. aeruginosa were shown against piperacillin, imipenem, cefotaxime, ceftriaxone, gentamicin, ceftazidime, aztreonam, and ciprofloxacin, respectively. seven isolates (9.2%) were esbl producers. more than 30% of the i...

Antibiotic resistance is a phenomenon in which antibiotic used to treat bacteria becomes useless due to resistance mechanism. Increased drug resistance and occurrence of Multiple Drug Resistance in bacteria specificity nosocomial and Urinary Tract Infection bacteria has reduced the possibilities of treating these infectious diseases. Efflux pumps are one of the major mechanism of MDR in bacteri...

drug resistance (especially multiple drug resistance) in mycobacterium tuberculosis makes global concerns in treatment and control of tuberculosis. rapid diagnosis of drug resistant strains of the bacteria has vital importance in the prognosis of the disease. the aim of this study was to identify the mutations responsible for drug resistance in mycobacterium tuberculosis strains derived from pa...

antibiotic resistance is a phenomenon in which antibiotic used to treat bacteria becomes useless due to resistance mechanism. increased drug resistance and occurrence of multiple drug resistance in bacteria specificity nosocomial and urinary tract infection bacteria has reduced the possibilities of treating these infectious diseases. efflux pumps are one of the major mechanism of mdr in bacteri...

OBJECTIVE To evaluate the resistance pattern of tuberculosis cases. METHODS A descriptive study was done in two out patient referral clinics from January 1999 to March 2003. All TB cases that had cultures positive for mycobacterium tuberculosis were evaluated. RESULTS Data from 71 proven culture positive patients was available. Resistance to at least one antituberculous drug was found in 44...

Multidrug resistance (MDR), which is mediated by multiple drug efflux ATP-binding cassette (ABC) transporters, is a critical issue in the treatment of acute leukemia, with permeability glycoprotein (P-gp), multidrug resistance-associated protein 1, and breast cancer resistance protein (i.e., ABCG2) consistently being shown to be key effectors of MDR in cell line studies. Studies have demonstrat...

background : due to the importance of the metal zinc as an essential biological element with known toxic properties, and considering the widespread secondary infections caused by pseudomonas aeruginosa strains with resistance to antibiotics and disinfectants, the present study aimed at exploring the antimicrobial properties of the metal zinc in both clinical and environmental multiple drug resi...